Renal Dosing For erectile dysfunction, a starting dose of 25mg should
Further information
If your medical doctor is using this medicine to treat your pain, your doctor or pharmacist may already be aware of any possible drug interactions and may be monitoring you for them. Do not start, stop, or change the dosage of any medicine before checking with your doctor, health care provider or pharmacist first. Sildenafil has serious interactions with at least 48 different drugs. Sildenafil has moderate interactions with at least 72 different drugs. This information does not contain all possible interactions or adverse effects.
Can I take Sildenafil Citrate as often as I want?
Therefore, before using this product, tell your doctor or pharmacist of all the products you use. Keep a list of all your medications with you, and share this information with your doctor and pharmacist. Check with your health care professional or doctor for additional medical advice, or if you have health questions, concerns or for more information about this medicine. Do not take Revatio or Viagra if you are allergic to sildenafil or any ingredients contained in this drug. In case of overdose, get medical help or contact a Poison Control Center immediately Soluble guanylate cyclase (sGC) stimulators (e.g., riociguat); concomitant use can cause hypotension Co-administration with nitrates (either regularly and/or intermittently) and nitric oxide donors Consistent with the effects of PDE5 inhibition on the nitric oxide/cyclic guanosine monophosphate pathway, PDE5 inhibitors may potentiate the hypotensive effects of nitrates A suitable time interval following PDE5 dosing for the safe administration of nitrates or nitric oxide donors has not been determined Elicits vasodilatory properties, resulting in mild and transient decreases in blood pressure.
Autres utilisations
See "What Are Side Effects Associated with Using Sildenafil?" Prolonged use may result in overgrowth of nonsusceptible organisms, including fungi See "What Are Side Effects Associated with Using Sildenafil?” Elicits vasodilatory properties, resulting in mild and transient decreases in blood pressure Use with caution in patients with anatomic deformation of penis (e.g., angulation, cavernosal fibrosis, or Peyronie disease), conditions potentially predisposing to priapism (e.g., sickle cell anemia, multiple myeloma, or leukemia), cardiovascular disease, bleeding disorders, active peptic ulcer disease, liver disease, renal impairment, multidrug antihypertensive regimens, retinitis pigmentosa, concomitant use of CYP3A4 inhibitors Pulmonary vasodilators may significantly worsen cardiovascular status of patients with pulmonary veno-occlusive disease Patients taking alpha blocker should be stabilized before starting phosphodiesterase (PDE)-5 inhibitor, which should be initiated at lowest dose; if patient is already taking optimized dose of PDE-5 inhibitor, alpha blocker should be initiated at lowest dose to avoid hypotension Not to be taken with other PDE-5 inhibitors Sudden decrease or loss of hearing, which may be accompanied by tinnitus and dizziness Viagra: Patients should stop sildenafil and seek medical care if a sudden loss of vision occurs in 1 or both eyes, which could be a sign of non-arteritic anterior ischemic optic neuropathy (NAION); use with caution, and only when the anticipated benefits outweigh the risks, in patients with a history of NAION; patients with a ”crowded” optic disc may also be at an increased risk of NAION Viagra: Potential for cardiac risk with sexual activity in patients with preexisting cardiovascular disease; therefore, treatment for erectile dysfunction generally should not be instituted in men for whom sexual activity is inadvisable because of their underlying cardiovascular status May cause dose-related impairment of color discrimination; use caution in patients with retinitis pigmentosa Evaluate underlying causes of erectile dysfunction or BPH before initiating therapy Revatio: In small, prematurely terminated study of patients with PAH secondary to sickle-cell disease, vaso-occlusive crises requiring hospitalization were more commonly reported by patients who received sildenafil than by those randomized to placebo; effectiveness of sildenafil in PAH secondary to sickle-cell anemia has not been established; the clinical relevance to men treated for erectile dysfunction with sildenafil is not known Revatio: Not for use in children with PAH; increased mortality with increasing doses (hazard ratio 3.5) was observed in randomized, double-blind, placebo-controlled clinical trial of 234 children (1-17 years) with PAH who had mild-to-moderate symptoms at baseline Revatio: Epistaxis occurred in 13% of patients with PAH secondary to connective tissue disease (e.g., scleroderma); this effect was not seen in idiopathic PAH; incidence was also higher in those receiving concomitant PO vitamin K antagonist therapy (9%) than in those not receiving such therapy (2%) Sildenafil may be acceptable for use during pregnancy Either animal studies show no risk but human studies are not available, or animal studies showed minor risks and human studies were done and showed no risk It is unknown whether sildenafil is distributed into breast milk. Simplify your healthcare journey with Indian Government's ABHA card. It belongs to the group Phosphodiesterase Type5 (PDE 5) Inhibitors. This pharmaceutical formulation is a combination of medicines used to treat erectile dysfunction. This formulation has been prepared from the Sildenafil; it increases the blood flow to the penis. be considered for patients with severe renal impairment (CrCl < 30).
| Brand Name | Manufacturer | Dosage Forms | Price Range (USD) | Available Regions |
|---|---|---|---|---|
| Viagra | Pfizer | 25, 50, 100 mg | 30-50 per tablet | Worldwide |
| Revatio | Pfizer | 20 mg tablets | 40+ per tablet | Mainly for pulmonary hypertension |
| Kamagra | Ajanta Pharma | 50, 100 mg | 0.5-2 per tablet | Asia, Middle East |
| Generic Sildenafil | Multiple manufacturers | 25, 50, 100 mg | 0.3-3 per tablet | Global |
Dosing adjustment guidelines have not been defined for patients with HD/PD.
- Sildenafil was first approved by the FDA in 1998.
- It revolutionized erectile dysfunction treatment worldwide.
- Research is ongoing into new potential uses of PDE5 inhibitors.
- The drug has helped millions improve their quality of life.
For pulmonary arterial hypertension, no adjustment
| Product | Dosage | Quantity + Bonus | Price | |
|---|---|---|---|---|
| Viagra Generic | 200mg | 30 + 2 Pills | 83.07€ 79.11€ | |
| Kamagra Polo | 100mg | 120 + 6 Pills | 327.15€ 311.57€ | |
| Viagra Generic | 25mg | 30 + 4 Pills | 47.97€ 45.69€ | |
| Viagra Generic | 50mg | 180 + 8 Pills | 158.82€ 151.26€ | |
| Viagra Generic | 100mg | 60 + 4 Pills | 96.36€ 91.77€ | |
| Viagra Generic | 150mg | 90 + 6 Pills | 147.18€ 140.17€ | |
| Kamagra Oral Jelly | 100mg | 30 + 5 Sachets | 136.20€ 129.71€ | |
| Viagra Generic | 150mg | 30 + 2 Pills | 72.32€ 68.88€ | |
| Kamagra Soft Tabs | 100mg | 60 + 4 Pills | 180.59€ 171.99€ | |
| Kamagra | 100mg | 20 Pills | 86.09€ 81.99€ | |
| Kamagra Polo | 100mg | 84 + 4 Pills | 244.49€ 232.85€ | |
| Viagra Generic | 200mg | 90 + 6 Pills | 170.79€ 162.66€ | |
| Kamagra Soft Tabs | 100mg | 84 + 4 Pills | 233.05€ 221.95€ |
is needed for patients with renal impairment.
8.1 Pregnancy
It should be taken at least 30 minutes before sexual activity and requires sexual stimulation to work. It can be taken before or after meals. Do not alter the recommended dose or duration without consulting your doctor. If you have any allergy to the content of medicine, inform your doctor. If you have any history of heart failure or blood pressure inform your doctor.
Does sildenafil interact with other medicines (drug interactions)?
Use the medicine as you remember to take. If the next dose is near then Skip the missed Dose. Do not double up for the missed Dose. If you miss a dose frequently then consult your Doctor. Erectile Dysfunction (ED) is when a man has trouble getting or keeping an erection firm enough for sex.
What are the serious side effects of sildenafil?
Pulmonary arterial hypertension is a form of high blood pressure that impacts the arteries in the lungs and the heart. It is given only for mens not for womens. It is given only for men's not for women's. It may sildenafil 100mg lowest price decrease alertness, affect your vision or make you feel sleepy and dizzy. Exercise caution when using it in individuals with kidney disease. Hepatic Dosing For erectile dysfunction, a starting dose of 25mg
Non-medical use
Adjustments to the dosage may be necessary, so it's important to seek advice from your doctor. It should be used with caution in patients with liver disease. Dose adjustment of medicine may be required. Sildenafil Citrate Tablets are a drug used in the treatment of sexual function problems (erectile dysfunction, impotence) in males. This medication is not a cure for erectile dysfunction.
Noms commerciaux
Sildenafil Citrate is also used to improve exercise capacity in patients with pulmonary arterial hypertension. The active ingredient works by preventing the enzyme phosphodiesterase type-5 from working. This relaxes the muscles and blood vessels and allows the flow of blood to increase to the penis during sexual stimulation. Sildenafil Citrate Tablets are produced with a dosage of 50mg or 100mg. This drug is available in 3 packaging options: a box containing a blister of 4 tablets, a box containing 100 tablets, or a bottle of 1000 tablets.
Viagra and foods
AdvaCare Pharma is a global distributor and manufacturer of Sildenafil Citrate Tablets. This medicine is produced in our GMP-certified facilities in China, India, and the USA. Our factories are routinely inspected to ensure they meet the high standards necessary to comply with WHO guidelines and standards. AdvaCare Pharma is a trusted Sildenafil manufacturer committed to providing quality-assured, cost-effective pharmaceuticals for an ever-changing global market. Manufacturing a wide range of 200+ pharmaceutical products in tablet form, we ensure that all of our oral solid dosage forms adhere to stringent GMP standards. should be considered for patients with hepatic impairment or cirrhosis.
Shipping & Delivery
We operate according to a unique "vested supplier-distributor relationship" business model, in which we tie our success in a market to that of our distributor. Such a model facilitates a closer relationship by working together to achieve pre-defined goals for market entry and expansion. As a Sildenafil manufacturer and global supplier, we implement unique strategies to ensure successful distribution. It liquid sildenafil citrate is used to treat erectile dysfunction in men. Sildenafil Citrate is also used to improve exercise ability and slow down the progression of pulmonary arterial hypertension in children and adults.
Does Viagra work to treat ED?
This medication is intended to be taken orally. It can be taken with or without food, but a high-fat meal may delay the drug's activity. Adult Dosing For erectile dysfunction, the usual dose is 25-100mg taken 30 minutes to 4 hours before sexual activity. It is recommended to consider a starting dose of 25mg in patients over 65 years old. For pulmonary arterial hypertension, the usual dose is 20mg taken 3 times per day.
Dysfonction érectile
Doses should be taken 4-6 hours apart. Geriatric Dosing For erectile dysfunction in patients 65 years or older, the usual starting dose is 25mg 30 minutes to 4 hours before sexual activity. The dose can be increased based on tolerance and effectiveness. The maximum dosage is 100mg per day. The dose can be increased up to 80mg taken 3 times per day. For pulmonary arterial hypertension, no adjustment is needed for patients with Child-Pugh Class A or B.
| Parameter | Value | Unit | Description |
|---|---|---|---|
| Tmax | 30-120 | minutes | Time to peak plasma concentration |
| Half-life | 3-5 | hours | Time for plasma concentration to halve |
| Bioavailability | ~40 | % | Amount absorbed unchanged |
| Protein Binding | 96 | % | Extent bound to plasma proteins |
Dosing adjustment guidelines have not been
- Sildenafil should be taken about 1 hour before sexual activity.
- It does not cause an erection on its own; arousal is needed.
- Food, especially high-fat meals, can delay the onset of action.
- Avoid grapefruit juice as it may increase sildenafil blood levels.
defined for patients with Child-Pugh Class C.
| Indication | Contraindication | Comments |
|---|---|---|
| Erectile dysfunction | Use of nitrates | Absolute contraindication |
| Pulmonary arterial hypertension | Severe cardiovascular disorders | FDA approved for PAH (Revatio) |
| Raynaud's phenomenon (off-label) | Hypersensitivity to sildenafil | Not FDA approved for this indication |
| Altitude sickness (off-label) | Concomitant use with alpha-blockers | Use cautiously under supervision |